Peter Heeringa Selected Research

Agammaglobulinaemia Tyrosine Kinase

12/2019

Evidence for enhanced Bruton's tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis.

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Peter Heeringa Research Topics

Disease

38	Inflammation (Inflammations) 04/2024 - 06/2002
35	Vasculitis (Vasculitides) 10/2023 - 10/2002
29	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 11/2023 - 01/2004
25	Glomerulonephritis 01/2023 - 03/2002
15	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 01/2020 - 10/2002
10	Giant Cell Arteritis (Horton Disease) 04/2024 - 07/2018
9	Autoimmune Diseases (Autoimmune Disease) 11/2023 - 12/2007
9	Atherosclerosis 01/2020 - 05/2002
6	Fibrosis (Cirrhosis) 04/2024 - 06/2002
6	Infections 04/2024 - 12/2010
6	Microscopic Polyangiitis 11/2018 - 10/2002
5	Systemic Vasculitis 01/2023 - 10/2004
5	Sepsis (Septicemia) 12/2018 - 04/2010
5	Ischemia 03/2013 - 02/2003
4	Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis) 09/2023 - 01/2022
4	Obesity 01/2023 - 01/2016
4	Acute Kidney Injury (Acute Renal Failure) 12/2018 - 10/2004
4	Albuminuria 01/2017 - 03/2008
4	Reperfusion Injury 10/2004 - 02/2003
3	COVID-19 04/2023 - 01/2022
3	Hemorrhage 10/2022 - 06/2002
3	Churg-Strauss Syndrome (Allergic Angiitis) 12/2013 - 07/2005
3	Nephritis 04/2013 - 07/2002
2	Pemphigus (Pemphigus Vulgaris) 03/2024 - 01/2023
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2023 - 09/2016
2	Critical Illness (Critically Ill) 01/2023 - 01/2022
2	Bites and Stings (Sting) 12/2022 - 10/2022
2	Insulin Resistance 01/2017 - 01/2012
2	Lupus Nephritis 09/2016 - 01/2016
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2016 - 01/2012
2	Atherosclerotic Plaque (Atheroma) 11/2013 - 06/2002
2	Hemorrhagic Shock 07/2013 - 09/2011
2	Shock 09/2011 - 08/2009
2	Kidney Cortex Necrosis 07/2005 - 10/2002
1	Thrombotic Thrombocytopenic Purpura 01/2023

Drug/Important Bio-Agent (IBA)

42	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2023 - 10/2002
28	Peroxidase (Myeloperoxidase)IBA 01/2022 - 10/2002
20	AutoantibodiesIBA 03/2024 - 10/2002
15	AntibodiesIBA 04/2024 - 01/2004
13	CytokinesIBA 09/2023 - 02/2004
13	Immunoglobulin G (IgG)IBA 01/2023 - 07/2002
10	Myeloblastin (Proteinase 3)IBA 01/2022 - 11/2005
9	LipopolysaccharidesIBA 01/2022 - 02/2003
7	Proteins (Proteins, Gene)FDA Link 03/2024 - 12/2007
7	Complement System Proteins (Complement)IBA 12/2018 - 02/2003
5	CholesterolIBA 05/2015 - 04/2010
5	LipidsIBA 05/2015 - 05/2002
5	E-SelectinIBA 01/2012 - 07/2007
4	Rituximab (Mabthera)FDA Link 03/2024 - 06/2014
4	AutoantigensIBA 01/2021 - 03/2011
4	Messenger RNA (mRNA)IBA 12/2018 - 08/2009
4	Serum Amyloid A Protein (Serum Amyloid A)IBA 11/2015 - 04/2010
3	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2020
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 04/2023 - 09/2006
3	Dexamethasone (Maxidex)FDA LinkGeneric 01/2023 - 07/2007
3	AdipokinesIBA 01/2023 - 01/2017
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2016
3	C-Reactive ProteinIBA 11/2021 - 01/2012
3	HMGB1 Protein (HMG1)IBA 12/2016 - 03/2013
3	Monoclonal AntibodiesIBA 09/2016 - 02/2003
3	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2016 - 12/2010
3	Apolipoproteins E (ApoE)IBA 05/2015 - 03/2011
3	antiglomerular basement membrane antibodyIBA 01/2013 - 08/2005
3	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2012 - 03/2011
2	Macrophage Colony-Stimulating FactorIBA 04/2024 - 01/2020
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 04/2024 - 01/2020
2	LeptinIBA 01/2023 - 01/2022
2	Polysaccharides (Glycans)IBA 01/2023 - 07/2010
2	Nucleic AcidsIBA 12/2022 - 10/2022
2	DNA (Deoxyribonucleic Acid)IBA 10/2022 - 06/2016
2	Pyruvate KinaseIBA 01/2022 - 01/2022
2	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 01/2020
2	Angiopoietin-2IBA 01/2022 - 03/2013
2	EnzymesIBA 01/2022 - 10/2004
2	Peptide Hydrolases (Proteases)FDA Link 11/2021 - 01/2004
2	CreatinineIBA 01/2019 - 01/2016
2	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2018 - 09/2006
2	Immune Checkpoint InhibitorsIBA 01/2018 - 01/2018
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 06/2016 - 08/2009
2	Catechin (Z 7300)IBA 01/2016 - 03/2014
2	Anthocyanins (Anthocyanin)IBA 01/2016 - 05/2015
2	EpitopesIBA 04/2013 - 03/2008
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2012 - 09/2011
2	NF-kappa B (NF-kB)IBA 03/2011 - 02/2004
2	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 05/2009 - 02/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2006 - 07/2005
1	Serine Proteases (Serine Protease)IBA 04/2024
1	fibroblast activation protein alphaIBA 04/2024
1	Interleukin-2 (IL2)IBA 04/2024
1	Interleukin-10 (Interleukin 10)IBA 04/2024
1	Desmoglein 3IBA 03/2024
1	Desmoglein 1IBA 03/2024
1	KinesinsIBA 10/2023
1	VaccinesIBA 04/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	Oxygen (Dioxygen)IBA 01/2023

Therapy/Procedure

8	Therapeutics 03/2024 - 09/2006
2	Artificial Respiration (Mechanical Ventilation) 01/2023 - 09/2011
2	Nephrectomy 12/2018 - 02/2003
1	Duration of Therapy 04/2024